Stimulation of
Ovaries
After determining the personalized treatment plan, ovarian stimulation is commenced on the second to fifth day of menstruation. For this purpose daily injections or pills are prescribed and used.
Drugs are used on a daily basis to stimulate the ovaries, the dose of which is assigned based on the patient’s ovarian reserve status, body mass index (calculated by the weight and height of the patient) and her previous response, if available. Ovarian reserve may not necessarily be correlated with chronological female age.
To assess ovarian reserve, we mainly use the so-called bilateral antral follicle count, which is the number of 2-10 mm sized follicles in both ovaries Follicular growth is monitored by frequently performed trans-vaginal ultrasonography and blood estradiol (E2) levels. There is no need for fastening before such testing. The daily dosage of drugs used to stimulate the ovaries is adjusted based on the results of trans-vaginal ultrasonography and E2. Our nurses give a call, usually in the afternoon, for such dose assignments. The patients only need to spend 15-20 minutes at our center for trans-vaginal ultrasonography and E2.
Final shut injection is performed when follicles reach 18-20 mm in diameter as assessed by trans-vaginal ultrasonography. Oocyte pickup procedure (OPU) is performed under light general anesthesia 34-36 hours later. The type of final shut injection is determined based on the ovarian response and will be decided by your physician. Treatment may be cancelled before final shut injection in around 10-15% cycles; the main reasons for cancellation are insufficient ovarian response due to diminished ovarian reserve and discordant follicular growth.
Drugs are used on a daily basis to stimulate the ovaries, the dose of which is assigned based on the patient’s ovarian reserve status, body mass index (calculated by the weight and height of the patient) and her previous response, if available. Ovarian reserve may not necessarily be correlated with chronological female age.
To assess ovarian reserve, we mainly use the so-called bilateral antral follicle count, which is the number of 2-10 mm sized follicles in both ovaries Follicular growth is monitored by frequently performed trans-vaginal ultrasonography and blood estradiol (E2) levels. There is no need for fastening before such testing. The daily dosage of drugs used to stimulate the ovaries is adjusted based on the results of trans-vaginal ultrasonography and E2. Our nurses give a call, usually in the afternoon, for such dose assignments. The patients only need to spend 15-20 minutes at our center for trans-vaginal ultrasonography and E2.
Final shut injection is performed when follicles reach 18-20 mm in diameter as assessed by trans-vaginal ultrasonography. Oocyte pickup procedure (OPU) is performed under light general anesthesia 34-36 hours later. The type of final shut injection is determined based on the ovarian response and will be decided by your physician. Treatment may be cancelled before final shut injection in around 10-15% cycles; the main reasons for cancellation are insufficient ovarian response due to diminished ovarian reserve and discordant follicular growth.